Title: The Beneficiary Effects of Intravenous Dexmedetomidine on the Duration of Spinal Anesthesia in a Tertiary Care Hospital in South Kerala
Authors: Dr Sajil M S, Dr Hari Krishnan. S
DOI: https://dx.doi.org/10.18535/jmscr/v6i10.02
Abstract
Background: Spinal anesthesia is commonly used in lower limb surgeries .Central mechanisms have been proposed to explain the prolongation of effect reported with the off-label use of dexmedetomidine as an adjuvant in local anesthetic admixtures. We evaluated whether IV dexmedetomidine can prolong the duration of sensory block associated with spinal anesthesia.
Objective: To evaluate the effect of intravenous dexmedetomidine on sensory regression, duration of motor block, hemodynamic profile, level of sedation and postoperative analgesia.
Methodology: 60 patients of ASA grade I and II were enrolled in this study after getting informed consent and institutional ethical board clearance and randomly allocated into two groups. Group D received intrathecal 0.5% Heavy Bupivacaine, followed by infusion of intravenous dexmedetomidine 1µg/kg bolus over 10 minutes followed by 0.5µg/kg/hr infusion, patients in group C received intrathecal 0.5% bupivacaine heavy followed by infusion of same volume of normal saline as placebo
Results: Two segment dermatomal regression was achieved at 135±23.9 in group D. The time at which first analgesic was given to the patients when VAS >3 achieved that is in group D at 135± 23.9 min whereas in Group C it was only 77.7±11.7
Keywords: Intravenous dexmedetomidine, postoperative analgesia,sensory regression, spinal block.
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