Introduction: Proptosis is the clinical manifestation of pathology that results in anterior displacement of the eyeball beyond the orbital margin. It is a common manifestation of wide variety of diseases of the structures in and around the orbit and in some systemic diseases.

Objective: The main objective of the study was to analyse the various causes for proptosis.

Material & Methods: 50 consecutive cases presenting in ophthalmology OPD with provisional diagnosis of proptosis, over a period of two years from May 2015 to April 2017, were included.Detailed ocular and systemic history, examination and relevant investigations were done in necessary cases. Also other related specialties opinion obtained whenever indicated for diagnosis.

Results: Males were more commonly affected. The age distribution showed clustering in 40-60 years age group. Inflammatory etiologies were the most common cause for proptosis accounting for 34% of cases, followed by neoplasm accounting for 32% of cases and infectious etiologies accounting for 16% of cases. 6% cases of proptosis had vascular etiology. Trauma constituted for 8% of cases. 4% of cases had Hydatid Disease.

Conclusion: Orbital lesions have diverse etiology and pathogenesis. This necessitates a spectrum of investigations for early and timely diagnosis of these cases. Delay in diagnosis of correct etiologic factors resulting in proptosis may cause threat to life and vision. Further studies with larger sample size are recommended.

Keywords:  Proptosis, Etiology, Exophthalmos, Orbit.

1. Moore, Keith L. Clinically Oriented Anatomy 6th Ed. Lippincott Williams & Wilkins. 2010ISBN 978-07817 7525-0.
2. Kumar V, Abbas AK, Fausto N. Robbins and Cotran Pathologic Basis of Disease. Seventh Edition. Philadelphia: Elsevier Saunders, 2005,1423.
3. Rootman J: Diseases of the orbit. Philadelphia, JB Lippincott, 1988, 1-162.
4. Naidu APR, Satya Srinivas V, Murali Krishna V, Madhuri P. Proptosis - A Clinical Profile. International Journal of scientific research and management. 2015; 3(3):2344-48.
5. Khan NH, Moin M, Khan MA, Azhar Hameed. Unilateral proptosis: a local experience. Biomedical. 2004;20:114-116.
6. Rauniyar RK, Thakur SD, Panda A, Sharma U. Radiological Evaluation of Orbit in cases of Proptosis in Eastern Nepal. NJR. 2011;1(1):8-14.
7. Loganathan M, Radhakrishnan M. An Etiological Analysis of Childhood Proptosis. Journal of Evolution of Medical and Dental Sciences 2014;3(22):6158-6162.
8. Amudhavadivu S, U. Vijaya Shanmugam. An Aetio-Epidemiological Inquiry of Proptosis. Int J Intg Med Sci. 2016; 3(10):439-442.
9. Masud MZ, Babar TF, Iqbal A, et al. Proptosis: Etiology and demographic patterns. J coll Physicians Surg Pak. 2006; 16(1): 38-41.
10. Zaidi S H et al. Unilateral proptosis in ENT practice. Journal Pakistan med. Assoc. 1991;41(10):248-250.
11. Kishor K Satpute, Chingsuingamba Y. A retrospective analysis of presentation and management outcome of proptosis in a tertiary care centre of North-East, India-a case series. IOSR Journal of Dental and Medical Sciences. 2013; 5(1):30-32.
12. Sabharwal KK, Chouhan AL, Jain S. CT evaluation of proptosis. Indian J Radiol Imaging 2006;16:683-8.
13. Sharma P, Tiwari PK, Ghimire PG, Ghimire P. NJMS. 2013;02(01):35-7.
14. Margo CE, Mulla ZD, Malignant tumors of the orbit. Ophthalmology 1998; 105: 185.

Dr Babita Sharma

Address- House No. D 103, Vinay Nagar, Sector 4, Gwalior (M.P.) Pin- 474012, India

Email: This email address is being protected from spambots. You need JavaScript enabled to view it., Mobile No- +91 9752533369