Title: Significance of C-Reactive Proteins (CRP) in the Prediction of Patients with Premature Rupture of Membranes
Authors: Dr Nayana Deb, Dr R.R. Sinha, Dr Satyendu Sagar
DOI: https://dx.doi.org/10.18535/jmscr/v6i6.158
Abstract
Objective: C-Reactive Proteins (CRP) is an indicator of Sub-clinical infection in cases of Premature Rupture Of Membrane (PROM). The aim of present study was, the estimation of CRP from the patients with premature rupture of membrane.
Materials and Methods: A total of 28 cases of Preterm, Premature rupture of membranes and 28 patients preterm with intact membranes, between 28-36 weeks of gestation were studied.
Results: The Sensitivity and specificity of CRP determination was found to be 82.6% each as an early predictor of subclinical chorioamnionitis. TLC had a low sensitivity of 20% and specificity of 60% in detecting histological chorioamnionitis (HCA).
Conclusion: CRP estimation is a reliable marker for detection of early chorioamnionitis at the same time, it is quite affordable and reasonably simple.
Keywords: PROM, CRP, Chorioamnionitis, Sensitivity, Specificity
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