Objective: Testicular fine needle aspiration cytology (FNAC) is an important investigation in management of male infertility, especially to differentiate between obstructive and non obstructive causes of azoospermia. It is less invasive and associated with no or minimal complications. Nowadays when assisted fertilization techniques are being practiced, fibrosis after biopsy may further hamper in sperm extraction for intra cytoplasmic sperm injection (ICSI). Present study was undertaken to evaluate and detailed analysis of aspiration cytology of Testes, in cases of male infertility and also it is compare with Testicular biopsy.

Materials and Methods: A total of 36 patients of male infertility were studied, from which 44 testicular aspiration was done and only 3 cases were subjected to testicular biopsy. Aspiration was done twice in 5 cases and thrice in 1 case.

Result: Out of 36 patients with male infertility, there were 32 cases of primary infertility and 4 cases of secondary infertility. Semen analysis showed oligospermia in 4 cases and 32 cases were Azoospermic. Spermatogenesis was present in 28 cases and absent in 6 cases and inadequate in 2 cases. Then all cases were reviewed according to five subcategories. Histological findings were compared with their cytological categories.

Conclusion: The Cytological diagnosis correlated well with histological diagnosis and helped in management of infertility. FNAC can help in management of surgical and medical causes of infertility and can save unnecessary expensive investigations in cases of sertoli cell only syndrome and atrophic patterns. FNAC in combination with semen analysis and serum follicle stimulating hormone levels are of great help in management of male infertility.

Keywords: Testes, FNAC, Biopsy, Infertility, Aspiration.

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Dr Sanjeev Kamal

Tutor, Department of Pathology,

Sri Krishna Medical College, Muzaffarpur, India