Title: Comparison of different renal function tests for detecting renal dysfunction in patients with Metabolic Syndrome
Authors: Gajraj Singh Yadav, R.C. Gupta, Manju Pandey
DOI: https://dx.doi.org/10.18535/jmscr/v6i6.73
Abstract
Background: Several renal function tests (RFTs) are used to detect renal dysfunction. Their relative reliability in detection of renal dysfunction in metabolic syndrome (MS) is unknown.
Objective: To compare different renal function tests for detection of renal dysfunction in patients with MS.
Material and Methods: The material comprised 279 adult patients with MS diagnosed according to NCEP: ATP-III criteria. RFTs done in all patients were serum creatinine, serum urea, creatinine clearance, eGFR and urine protein.
Results: Serum creatinine and serum urea were above normal in 32.26% of patients. Patients with eGFR below normal were 73.84%. Creatinine clearance was below normal in 61.29%. 18.99% of total subjects tested positive for urine protein.
Conclusion: Prevalence of renal dysfunction was high (73.84%) in patients with MS. eGFR appeared to be the best indicator of renal dysfunction.
Keywords: Metabolic syndrome, renal dysfunction, renal function test.
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