Title: Fine Needle Cytology of Thyroid in a Tertiary Care Hospital
Authors: Dr Kalpana. A. Deshpande, Dr Amruta A. Patil, Dr Sameer A. H Ansari
DOI: https://dx.doi.org/10.18535/jmscr/v6i5.154
Abstract
Background: Thyroid fine needle aspiration cytology is a valuable tool used for diagnosing and classifying thyroid lesions.
Material and Methods: The present prospective cytological study of thyroid lesions by fine needle aspiration was undertaken in the Department of Pathology from July 2010 to June 2012.A detailed clinical history was obtained before aspiration. Wet fixed smears were stained with haematoxylin and eosin and papanicolaou. Air dried smears were stained with May-Grunwald Giemsa stained.
Result: Out of 543 adequate thyroid aspirates,144 (52.74%) cases of goitre, 72 (26.37%) cases of thyroiditis, 4 (1.46 %) cases of Grave's disease, 1 (0.36%) case of thyroid cyst, 28 (10.25%) cases of indeterminate neoplasm and 25 (9.15%). cases of malignancies.
Conclusions: FNAC plays a pivitol role in diagnosing thyroid lesions, classifying them into benign and malignant and also to study the salient features of each lesion.
Keywords: thyroid, neoplasm, goitre, neck mass, malignancy, fine needle aspiration cytology.
References
- Philip S. Fieldman et al: Fine needle aspiration in squamous cell carcinoma of the Head and Neck. Archives Otolaryngol. 1983; 109: 735-742.
- Abrari A, Ahmad SS, Bakshi V. : Cytology in the Otolaryngologist’s domain- A study of 150 cases, emphasizing diagnostic utility and pitfalls:Indian Journal og Laryng Head and Neck Surgery; 2:21-9
- Rakhshan A. Rakshan M.The diagnostic accuracy of FNAC in head and neck lymphoid masses. Iranian Journal of Pathology. 2009;4:147–50.
- Wilson J.A. McIntyre MA. Vonon Haacke P. Et al. Fine needle aspiration cytology and Otolaryngologist. J.Laryngol Otol. 1987;101 (6):595–600.
- Bardales RH, Baker SJ, Mukunyadzi P. Fine needle aspiration cytology findings in 214 cases of nonparotid lesion of the head. Diagncytopathol 2000 Apr; 22(4):211-7.
- Frable WJ Frable MA. Thin-needle aspiration biopsy: the diagnosis of head and neck tumors revisited. Cancer. 1979 Apr;43(4):1541-8.
- Friedman M., Shimaoka K., Getaz P. Needle aspiration of 310 thyroid lesions. ActaCytol 1979; 23: 194-203.
- Chu E.W., Hanson T.A., Goldman J.M., Robbins J. Study of cells in fine needle aspirates of the thyroid gland. ActaCyto 1979; 23 (4) : 308-314.
- Mandrekar S.R., Nadkarni N.S. Role of fine needle aspiration cytology as the initial modality in the investigation of thyroid lesions. ActaCytol. 1995; 39: 898-904.
- Nguyen G.K., Ginsberg J. Fine-needle aspiration biopsy Cytology of the thyroid. Its value and limitations in the diagnosis and management of solitary thyroid nodules. Path. Ann.I91 : 63-91.
- Brauer R.J., Silver C.E. : Needle aspiration biopsy of thyroid nodules. Laryngoscope 1984; 94(1) : 38-42.
- Bouvet M., Feldman J.I. Surgical management of the thyroid nodule : Patient selection based on results of fine-needle aspiration cytology. Laryngoscope 1992; 102 : 1353-1356.
- Friedman M., Shimaoka K., Rao V. Diagnosis of chronic lymphocytic thyroiditis (Nodular presentation) by needle aspiration. ActaCytol. 1981 ; 25: 513-522.
- Ahmad T, Naeem M, Ahmad S, Samad A, Nasir A. Fine needle aspiration cytology (FNAC) and neck swellings in the surgical outpatient. [Internet]. Journal of Ayub Medical College, Abbottabad : JAMC. p. 30–2. Available from: http://www.ncbi.nlm.nih.gov/pubmed/19610510.
- Kung T. M., Yuen W. S.: Fine needle aspiration of the thyroid. Distinction between colloid nodules and follicular neoplasms using cell blocks and 21 gauge needles. ActaCytol. 1989; 33: 53 -60.
- Parveen K, Barua AR, Hossain A, Zaman J, MomenA.Value of FNAC in diagnosis of different types of thyroiditis and its comparison with clinical and biochemical findings. Mymensingh Med J.2009 Jul;18(2):250-4.
- Amatya BB, Joshi AR, Singh SK, Panth R, Basnet RB. A study of fine needle aspiration cytology of head and neck masses and their corroboration by histopathology. PMJN 2009;8(2)
- Handa U., Sukant G., Harshmohan, Nagarkar N. et al. Role of fine needle aspiration cytology in a management of thyroid lesion. A study on 434 patients. National Journal of Medical Research. 2008; 25;13-17.