Title: Spontaneous Lower Extremities Swelling Following Albendazole Therapy in a case in Neurocysticercosis

Authors: Abhishek Kumar, Prashant Kumar, Kuljeet Singh Anand, Jyoti Garg

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i5.153

Abstract

Human cysticercosis is important cause of seizure and neurological morbidity in developing countries. Cysticercosis result in human, after ingestion of the eggs of Taenia soleum usually after a close contact with a tapeworm carrier. The usual sites for the development of cyscticerci are the central nervous system (neurocysticercosis – NCC), subcutaneous tissue, skeletal muscle, heart muscle, and the eye. Antiparasitic treatment associated exacerbation of the inflammatory response in brain, eye or subcutaneous tissue is well known. Here we are reporting a case of NCC who developed severe swelling of lower limbs following albendazole therapy. She was treated with high dose of steroid with subsequent resolution of swelling. Therefore one must be vigilant about this rare complication.

Keywords: Neurocysticercosis ,Albendazole,Cerebral cyst, Ccorticosteroid, Anaphylactic reaction).

References

  1. White AC., Jr Neurocysticercosis : updates on epidemiology, pathogenesis, diagnosis, and management. Annu Rev Med. 2000; 51:187–206.
  2. Cruz I, Cruz ME, Carrasco F, Horton J. Neurocysticercosis : optimal dose treatment with albendazole. J Neurol Sci. 1995;133:152–154.
  3. Anand KS, Abraham J, Gowda S, Ratnakar C. Appearance of New Cysticer- cosis Nodules with Albendazole Therapy. Indian Journal of Pharmacology, 1994; 262: 165.
  4. Proaño JV, Madrazo I, Avelar F, López-Félix B, Díaz G, Grijalva I. Medical treatment for neurocysticercosis characterized by gaint subarachnoid cysts. N Engl J Med. 2001;345:879–885
  5. Sotelo J, Del Brutto OH. Brain cysticercosis. Arch Med Res. 2000;31:3–14.

Corresponding Author

Dr Abhishek Kumar

Department of Neurology, Max Superspeciality Hospital (west Block), Saket, New Delhi 110017, India

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