Title: Cord blood Hemoglobin and Red Blood Cell Indices in Term, Term IUGR and Preterm Babies in Northern Kerala – A comparative study
Authors: Jowhara.P.V, Ashraf.T.P, Ahammed Naseem V.H
DOI: https://dx.doi.org/10.18535/jmscr/v6i5.83
Abstract
Background: Cord blood Hemoglobin and Red Blood Cell Indices are frequently done in newborn babies as a part of routine evaluation. About one third babies are born pre term in India.
Objectives: This study was undertaken to establish the reference values of Hemoglobin & Red blood cell indices among Term babies with normal birth weight, Term Intra uterine growth restricted babies (Term IUGR) and preterm babies, and to compare the values each other to find out any significant difference.
Materials and Methods: Umbilical cord sample were taken from 210 babies, 70 of them belongs to each group, Hemoglobin and Red Blood Cell Indices detected. The data obtained was analyzed with SPSS version 16.
Results and Conclusion: Mean Hb and haematocrit values were lowest in preterm babies and highest for term IUGR babies. There is statistically significant increase in RBC countas as the gestational age increases. There is further increase in RBC count in term IUGR babies. MCV and MCH were more preterm babies when compared term babies. MCHC is more in preterm babies and significant increase in RDW in term IUGR babies. The reference values obtained can be used as background data for proper management of neonatal period.
Keywords: Red blood cell, term, preterm, intra uterine growth restriction., hemoglobin, RBC indices.
References
- Wilcox AJ: On the importance and the unimportance of birth weight. International Journal of Epidemiology 30: 1233–1241. PMID: 11821313/2001. Sharma SR, Giri S, Timalsina U, Bhandari
- SS, Basyal B, Wagle K, et al. (2015) Low Birth Weight at Term and Its Determinants in a Tertiary Hospital of Nepal: A Case-Control Study. PLoS ONE: e0123962 doi:10.1371/ journal.pone.0123962.
- Stoll JB, Kliegman: The high risk infant. Nelson Textbook of paediatrics. Philadelphia, WB Saunder Company. 2004.5472-5450p
- Sharma et al. Intrauterine Growth Restriction: Antenatal and Postnatal Aspects. Clinical Medicine Insights: Pediatrics 2016:10 67–83 doi: 10.4137/CMPed.S40070.
- World Health Organization. Focusing on anaemia: Towards an integrated approach for effective anaemia control. Joint statement by the World Health Organiz-ation and the United Nations Children’s Fund. Available at:www.who.int/topics/anaemia/en/who.unicef-anaemiastatement.pdf. Accessed on June 10, 2007.
- Vassilios Katsares et al: Reference Ranges for Umbilical Cord Blood Hematological Values. July 2009 j Volume 40 Number 7 j LABMEDICINE. p437-439.
- Singh M: Care of the New born. Sagar publication. 4th edition,1991; p112,120,121,157.
- Noguera NI et al: Hematologic study of newborn umbilical cord blood. Medicina (B Aires). 59(5 pt 1):446-8,1999.
- D’souza SW et al: Haematological value in cord blood in relation to foetal hypoxia. Br J Obstet Gynaecol. 88(2): 129-32, 1981 Feb.
- Boulot P et al: Hematologic values of foetal blood obtained by means of cordocentesis. Fetal Diagn Ther 8(5):309-16,1993 Sep-Oct.
- Haworth JC et al: Relation of blood glucose to hematocrit, birth weight and other body measurements in normal and rowth retarded newborn infants. Lancet 2:907,1967.
- Camitta MB: The anemias. Nelson Text book of paediatrics, 15th edition. Behrman,Philadelphia. WB Saunder Company p1378,1996.