Leiomyosarcoma is a rare aggressive soft tissue tumor derived from smooth muscle cells usually of uterine, gastrointestinal or soft tissue origin. Ten cases of leiomyosarcomas presenting at various sites were retrospectively reviewed. Four were of uterine origin, three were located in the extremeties involving the thigh, gluteal and perianal region respectively and single case of retroperitoneal origin was found. Two rare cases of scrotal and colonic leiomyosarcoma were also included. Age of the patients ranged from 40-68 years with a male: female ratio of 3:7 respectively. Uterine and retroperitoneal leiomyosarcomas were larger, higher grade, and more commonly associated with synchronous metastases.  Although larger and higher grade, retroperitoneal and uterine LMS share similar survival and recurrence patterns with their trunk and extremity counterparts. Presence of metastatic disease remained the most important prognostic factor. Extensive studies including large number of cases need to be done for setting definitive treatment protocols for these aggressive neoplasms

Keywords: Leiomyosarcoma, aggressive, neoplasms, prognosis.

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Dr Vipul Bansal

Department of Radiation Oncology, Regional Cancer Centre,

Pt BD Sharma University Of Health Sciences

Rohtak, Haryana, India

Telephone No. 9718772333, Email: This email address is being protected from spambots. You need JavaScript enabled to view it.