Background: Perforation peritonitis with effect of tobacco delays the healing of gastric duodenal ulcer and increases the risk of peptic ulcer is one of the commonest surgical emergencies encountered by surgeons all over the world. The aim of this study is to examine and compare the case of perforation peritonitis and found the relationship of tobacco with that of peptic perforation.

Material and Method: This clinicopathological study was examined 250 patient of perforation peritonitis. Who were admitted in ward of the department of surgery in Gandhi Medical College and, associated Hamidia Hospital Bhopal (M.P.) from August 2010 to November 2011.

Results: Out of total 250 patients 142 gastric perforation and 108 was intestinal perforation. Out of 142 gastric perforations patient 120 were tobacco user, while only 37 patients were tobacco user out of 108 patient of the intestinal perforation. Patients with perforation peritonitis were mostly in age group of 40-49 years. Postoperative complications were significantly higher in gastric perforation with tobacco use as compared to cases with intestinal perforation with tobacco use. Postoperative complication is significantly higher in the patient who used tobacco in both from smoking and chewing in compare to single from among perforation. Average day of hospital stay were significantly higher in patient of gastric perforation (13.94 days) with tobacco use as compared to intestinal perforation (18.4 days) with tobacco use. Average day of hospital stay were significantly more in cases with tobacco user (11.19 days) as compared to non-user (8.1 days).

Conclusion: Our study shows that gastric perforation is more common in tobacco user group in comparison to non-tobacco user and intestinal perforation group.

Keyword: Perforation; Peritonitis; Gastric; Intestinal; Tobacco.

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