Title: Efficacy of bone marrow examination techniques in diagnosing chronic myeloid leukemia cases
Author: Himanshu Chauhan
DOI: https://dx.doi.org/10.18535/jmscr/v6i5.54
Abstract
Background: Bone marrow aspiration biopsies are conducted not only for carrying out cytological assessment but also for immunophenotypic, cytogenetic, molecular genetics, and other specialised investigations. Hence; we planned the present study to evaluate and compare the effectiveness of bone marrow aspiration, imprint and biopsy in patients suffering from chronic myeloid leukemia (CML).
Materials & Methods: We planned the present study to compare the effectiveness of bone marrow aspiration, imprint and biopsy in patients suffering from various haematological disorders. A total of 10 cases of CML were included in the present study. Complete demographic and clinical details of all the patients were obtained. Findings of bone marrow aspiration (BMA), Bone marrow imprint (BMI) and bone marrow biopsies (BMY) were compared. All the results obtained were subjected to statistical analysis by SPSS software.
Results: A total of 10 subjects diagnosed with CML were included in the present study. Among these 10 subjects, 6 were males while the remaining 4 were females. In 7 out of 10 cases, findings of BMA, BMI and BMY were in concordance with each other.
Conclusion: All the three bone marrow examination techniques are complementary top each other.
Keywords: Bone marrow aspiration, Bone marrow biopsy, Bone marrow imprint
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