Title: Prevalence of Co morbidities among patients having Multi Drug Resistant Tuberculosis: A Retrospective Analysis

Authors: Dr Kamendra Singh Pawar, Dr Ramakant Dixit

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i4.168

Abstract

The comorbid conditions may have both impact as risk factor for developing MDR TB and they may influence the treatment outcomes as well. This study was planned with an objective of determining the prevalence of co morbid conditions associated with MDR-TB at the time of treatment initiation at Drug Resistant Tuberculosis Centre, Ajmer (Rajasthan), India. Data was extracted by reviewing of medical records of MDR-TB patients maintained at DR-TB centre retrospectively. Data of 127 patients were found eligible for study. There were 101 (79.5%) males and 26(20.4%) females with mean age of study group was 38.6 years (with C.I.(95%) of mean±2.27). Mean pre-treatment BMI was 15.81 Kg/m2 (C.I (95%) of mean was ±0.40). Among these 127 patients, comorbid conditions were present in 51 (40.1%) patients. Among patients with comorbidities, majority of patients had single comorbid illness (n=43, 84.3%) while 8 (15.6%) patients were having dual comorbidities. Among single comorbid states, COPD was found most common (n=16, 31.3%). In conclusion, great proportion of patient with MDR TB in our study were found to have comorbid conditions. Proper identifications and management of such concurrent medical conditions is vital as they may affect outcome of treatment which itself is challenging.

Keywords: MDR-TB, Comorbid conditions, Outcome.

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