There are several natural occurring antioxidants in our body which serve to counteract against free radicals generated in our body as byproducts of various metabolic reactions. Any deficiency of these antioxidant in body would lead to increased free radical damage at cellular level which may contribute to mutations leading to oncogenesis. Majority of cancers have been shown to have some imbalance in antioxidants levels. Free radicals- antioxidant imbalance, if proven, may highlight the importance of antioxidant supplementation in prevention and as an adjunct to treatment of cancer. Here we attempt to study antioxidant enzymes namely- superoxide Dismutase, Catalase and Glutathione peroxidase, level in breast cancer patients to find any association with cancer.

Keywords: Breast cancer, Antioxidants, free radicals, Superoxide Dismutase, Catalase, Glutathione peroxidase.

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Parijat Suryavanshi

Department of General Surgery,

King George’s Medical University, Lucknow, India