Title: Study of Liver in Post Mortem Cases in Tertiary Care Centre – A Study of 4 Years

Authors: Dr Shailendra Singh Thakur, Dr Vipin Todase

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i3.221

Abstract

Post mortem evaluation of the liver has been very useful in reaching the diagnosis of patient cause of death.

Autopsy studies provide us with useful baseline data to start a step towards finding cause of death. The study was conducted in the department of Pathology, M.G.M Medical College, Indore (M.P) from 2013 to 2017. Liver specimens were collected from 127 cases of post mortum as a part of examination of multiple viscera, over a period of 4 years. Sections from representative area were submitted for processing, sectioned and stained with Hematoxylin and Eosin stain. The present study was retrospective study. It is observed that 127 cases were evaluated out of which 85 (66.93%) were males and 42 (33.07%) were females. Out of 127 specimens, 31(24.40%) are cases of normal liver morphology followed by chronic venous congestion 41 (32.28%) cases, fatty change 26 (20.47%) cases,, steatohepatitis hepatitis 18 (14.5%) cases, cirrhosis 10 (7.87%) cases, Metastasis in 01 (0.78%)case. The aim of the study was to study spectrum of histopathological lesions encountered in liver autopsy. In this autopsy study of 127 cases of liver specimens, the diagnosis found are fatty change, chronic venous congestion, portal triaditis and cirrhosis were the main findings and metastasis to liver was reported in one case.

Keywords: Alcoholic Cirrhosis; Liver; autopsy.

References

  1. Rezek R, Philipp and Max Millard: In autopsy pathology, Springfield, Thomas. 963; 464-467.
  2. John T Galambos: Liver in 4th Ed. Gastroenterology, WB Saunders Company, Philadelphia. 1985; 2985-3048.
  3. Alagarsamy J, Muthureddy Y et al. Incidentally discovered diseases – An Autopsy Study of Fifty Cases. International Journal of Science and Research.2014; 3(5):1332.
  4. Thamil Selvi R, Selvam V et al. Common Silent Liver Disease In and Around of Salem Population: An Autopsy Study. Journal of Clinical and Diagnostic Research.2012;6 (2):207-10.
  5. Singal P,Kaur M, D eepika. Incidental Findings in Autopsy Examination of Liver : A Study of 70 Cases .Ann.  Int. Med. and Den. Res. 2017;3(3),PT30-PT32.
  6. Desmet V, Rosai J. Liver : Rosai and Akerman’s Surgical Pathology. Vol 1.St Louis,USA : Elsevier Mosby; 2004:925-940.
  7. Rosoul Sotoudehmanesh, Masoud Sotodueh, Ali Ali- Asgari ,et al. Silent liver diseases in Autopsies from Forensic Medicine of Tehran. Archives of Iranian Medicine, 2006; 9 (4): 324-28.

Corresponding Author

Dr Vipin Todase

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