Title: Lipid Profile of Blood and Bile in Patients with Gall Stone Disease

Authors: Dr Harpreet Kaur, Dr Jaspreet Singh Dil, Dr Harkomal Kaur, Dr Jaspreet

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i3.178

Abstract

Introduction

Cholelithiasis is the commonest disease affecting the gall bladder, which is a major cause of upper abdominal emergencies1,2.Various constituents of gall stones include cholesterol, bilirubin, calcium, triglycerides, fatty acids, phospholipids and proteins3,4. These stones may be classified as cholesterol, pigment and mixed stones5 of which mixed stones constitute the majority and pure cholesterol stones being a rarity6. Researchers have tried to understand the pathogenesis of stone formation. Super saturation and concentration of bile, crystal nucleation and gall bladder dysmot-ility have been implicated as aetiological factors7.

Supersaturation of bile with cholesterol is found to be the most significant factor for formation of cholesterol stones8,9

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Corresponding Author

Dr Harpreet Kaur

GMC Amritsar