Title: Assessment of Lipid Profile of Patients with Acute Myocardial Infarction: A Comparative Study
Author: Mukesh Gupta
DOI: https://dx.doi.org/10.18535/jmscr/v6i3.81
Abstract
Background: Cardiovascular disease is regarded as a multifactorial disease, which affected by the environment and genetic factors. A growing evidences indicates that elevated concentrations of TG, TC, LDL-C and decreased HDL-C accelerate the development of atherosclerotic plaques. Hence; we planned the present study to assess the levels of mean serum lipid profile in AMI patients.
Materials & Methods: The present study included assessment of serum lipid profile in AMI patients. A total of 20 AMI patients and 20 aged matched controls were included in the present study. After overnight fasting, venous blood was collected from all the subjects in serum separator Vaccutainer tubes. We evaluated the levels of serum total cholesterol and serum triglycerides by using an Autoanalyzer. All the data were recorded on excel sheet. SPSSs software was used for the assessment of level of significance.
Results: A total of 20 AMI patients and 20 normal were included in the present study. Significant results were obtained while comparing the mean TC levels and HDL levels in patients of the AMI group and control group.
Conclusion: Risk of AMI is not prevented by reduction in the mean serum cholesterol levels.
Keywords: Acute myocardial infarction, Lipid profile.
References
- Biorch G., Blomquist G., Sievers J. Cholesterol values in patients with myocardial infarction and normal control group. Acta. Med. Scand. 1957;156:493–497.
- Bjorntrop P., Malmcrone R. Serum cholesterolin patient with myocardial infarction in younger ages. Acta. Med. Scand. 1960;168:151–155.
- Dodds C., Mills G.L. Influence of myocardial infarction on plasma lipoprotein concentration. Lancet. 1959;i:1160–1163.
- Tokuda Y. Risk factors for acute myocardial infarction among Okinawans. J Nutr Health Aging. 2005;9:272–6.
- Woo J, Ho SC, Wong SL, et al. Lipids, lipoproteins and other coronary risk factors in Chinese male survivors of myocardial infarction. Int J Cardiol. 1993;39:195–202.
- Lehto S, Palomaki P, Miettinen H, et al. Serum cholesterol and high density lipoprotein cholesterol distributions in patients with acute myocardial infarction and in the general population of Kuopio province, eastern Finland. J Intern Med. 1993;233:179–85.
- Nayak SB, Pinto Pereira LM, Boodoo S, et al. Association of troponin T and altered lipid profile in patients admitted with acute myocardial infarction. Arch Physiol Biochem. 2010;116:21–7.
- Zhong et al. Serum lipid profiles in patients with acute myocardial infarction in Hakka population in southern China. Lipids in Health and Disease. 2017;16:246.
- Shrivastava AK, Singh HV et al. Serial measurement of lipid profile and inflammatory markers in patients with acute myocardial infarction. EXCLI Journal 2015;14:517-526 – ISSN 1611-2156.
- Khan HA, Alhomida AS, Sobki SH. Lipid Profile of Patients with Acute Myocardial Infarction and its Correlation with Systemic Inflammation. Biomarker Insights. 2013;8:1-7.