Aims & Objective: Our study aims to evaluate the survival index of leukemia Patients on the basic of  cytochemical staining intensity and platelets count for  heamatological neoplasm. Concomettent effect of both ancillary technique are simple and cheaper method to confirm the diagnosis and prognosis with survival indexing.

Material & Methods: Fifty eight patients with suspected clinical and haematological leukemia  visiting the central pathology laboratory of medical college were studied .The study used morphology, cytochemical staining of myeloperoxidase (MPO), Sudan black (SBB), periodic acid Schiff (PAS) stain and leukocyte alkaline phosphates staining of blood smear to confirm the diagnosis of leukemia A complete blood counting including HB%,PCV, Red cell indices ,platelet count, total white cell count and PDW  was done by  Automated blood  cell counter.

Conclusion: In our study, cytochemistry helped in diagnosis of 62.5 % of AML, 84.2% of ALL, 14.3% of CML, none in CLL in addition to morphology in suspected cases of leukemia. Those leukemia have cytochemical positive high intensity with low to variable platelets counts have poor prognosis due to poor survival index..

Keyword: leukemia, cytochemical staining intensity, PDW.

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Dr Sachin Sharma

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