Title: A Histopathological Study of Biopsy Samples of Interface Dermatitis Obtained from Patients Attending Dermatology Department
Authors: Dr Amrita Sinha, Dr Vivek Gupta, Dr Sunil Gupta
DOI: https://dx.doi.org/10.18535/jmscr/v6i2.201
Abstract
Objective: To determine the histomorphological changes associated with various types ofinterface dermatitis (ID) and to correlate the clinical features with the histological diagnosis.
Methods: This was a observational study. A total of 100 patients were included in the study. Nail clippings for fungal culture, skin biopsy for histopathology, pus for culture and sensitivity were also recorded as and when required. A dermatologist examined all of the patients for examination of the skin, hair, nail, and mucosal tissues. Culture and biopsy of the lesions were done if needed. Pathologic examinations were done on specimens with hematoxylin-eosin staining.
Results: Most of the patients were in the age band of 21-30 (39%). More than half of patients were females (67%). Epidermis hyperkeratosis was most common (76%). Lichen planuspilaris was diagnosed in 18.0% patients. Oral Lichen planus was diagnosed in 6% patients.
Conclusion: It is concluded that histopathology is a dependable tool for identifying the underlying cause in lichenoid eruptions, for an early diagnosis and the appropriate treatment.
Keywords: Interface dermatitis, Dermatology, Histomorphological,
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