Title: Histopathological Spectrum of Kidney Lesions in Autopsy – A Study of 100 Cases
Authors: Amandeep Kaur, Vijay Kumar Bodal, Puneet Garg, Akashdeep Aggarwal
DOI: https://dx.doi.org/10.18535/jmscr/v6i2.150
Abstract
Background: Determination of cause of death particularly when the death occurred suddenly, unexpectedly, or in the young, is an important part of forensic autopsy practice. Performance of a complete and thorough autopsy on apparent deaths can provide invaluable information in the interest of public health. by identifying risks and monitoring disease trends. It provides the opportunity to discover new diseases, to evaluate toxic effects of drugs and therapies. The kidneys are often affected by chronic inflammatory lesions, neoplasm, toxic effects of various drugs and metabolic disorders.
Material and Methods: The present study was conducted on kidney specimens of 100 routine autopsies received in the department of pathology, Government Medical College, Patiala, Punjab to find out the frequency of various renal lesions in autopsy. All the histological sections were stained in H & E stain & mounted. All the histological sections were examined microscopically & findings were recorded and tabulated.
Results: The age range of the autopsies was between 25 and 80 years. 80 of the 100 autopsies were males, while 20 were females. In 25(25%) cases, the microscopic morphology was close to normal histology. Remaining 75 (75%) cases had a pathological findings at autopsy. Non glomerular nephropathies (58 %) were higher as compared to that of glomerular lesions (17%). In 17 cases of renal autopsies glomerular alterations were observed such as focal segmental glomerulosclerosis, nodular glomerulosclerosis and mesengial cell proliferation.
Keywords: Autopsy, Histopathology, Renal lesions.
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