Fluid and electrolyte balance is the most important parameter that maintains the normal homeostasis in the body. It is also important for the normal functioning of the cells and maintenance of acid-base balance in the body. Electrolyte disturbances are commonly present in most of the clinical disorders, so its correction is needed in the management of these diseases. The present study was conducted on the patients admitted in the emergency department of Government Medical College, Jammu in which the serum electrolytes and serum urea and creatinine levels were estimated to observe the prevalence of electrolyte abnormalities in these patients. It was observed that the hyponatremia is the most common electrolyte imbalance present in our study. Thus in the management of the patients admitted in emergency, the estimation of renal function tests and electrolytes should be done. As fluid therapy is the most common line of management in these patients while treating them the electrolyte abnormalities should be taken into consideration and should be treated accordingly.

Keywords: electrolytes, renal function tests, electrolyte abnormalities, hyponatremia.

1. Balci AK, Koksal O, Kose A, Armagan E, Ozdemir F, Inal T, et al. General characteristics of patients with electrolyte imbalance admitted to emergency department. World J Emerg Med. 2013; 4(2): 113-16.
2. Bockenkamp B, Vyas H. Understanding and managing acute fluid and electrolyte disturbances. Current Paediatrics 2003; 13:520–28.
3. El-Sharkawy AM, Sahota O, Maughan RJ, Lobo DN. The pathophysiology of fluid and electrolyte balance in the older adult surgical patient. Clinical Nutrition. 2014; 33: 6-13.
4. Goldberg A, Hammerman H, Petcherski S, Nassar M, Zdorovyak A, Yalonetsky S, et al. Hyponatremia and long-term mortality in survivors of acute ST-elevation myocardial infarction. Arch Intern Med. 2006; 166: 781–86.
5. Upadhyay S, Bhalerao N, Pratinidhi SA. Study of level of consciousness and electrolyte abnormalities in patients admitted to intensive care unit (ICU). Int J Contemp Med Res. 2017; 4(8): 1739-42.
6. Hawkins RC. Age and gender as risk factors for hyponatremia and hyperna-tremia. Clin Chim Acta. 2003; 337:169-72.
7. Alshayeb HM, Showkat A, Babar F, Mangold T, Wall BM. Severe hypernatremia correction rate and mortality in hospitalized patients. Am J Med Sci. 2011; 341: 356- 60.
8. Durst RA, Andersen OS. Electrochemistry. In: Burtis CA, Ashwood ER, editors. Teitz fundamentals of clinical chemistry, 5^th Philadelphia: Saunders; 2002.p.104-20.
9. Rose CFM. The estimation of urea by urease method in fluoride blood. Br J Exp Pathol. 1933; 14:339-42.
10. Husdan H, Rapoport A. Estimation of creatinine by the Jaffe reaction: a comparison of three methods. Clin Chem. 1968; 14: 222-38.
11. Herrod PJ, Awad S, Redfern A, Morgan L, Lobo DN. Hypo- and hypernatraemia in surgical patients: is there room for improvement? World J Surg. 2010; 34: 495-99.
12. Waikar SS, Mount DB, Curhan GC. Mortality after hospitalization with mild,moderate, and severe hyponatremia. Am J Med. 2009; 122: 857-65.
13. Anderson RJ, Chung HM, Kluge R, Schrier RW. Hyponatremia: a prospective analysis of its epidemiology and the pathogenetic role of vasopressin. Ann Intern Med. 1985; 102: 164- 68.
14. Laczi F. Etiology, diagnostics and therapy of hyponatremias. Orv Hetil. 2008; 149: 1347-54.

Dr Pallavi Mahajan

Demonstrator, Department of Biochemistry,

Government Medical College, Jammu, J&K

Phone no. 9419114012, Email: This email address is being protected from spambots. You need JavaScript enabled to view it.