Title: Clinical Profile & Management of Gastrointestinal Stromal Tumor (GIST)

Authors: Sarat Chandra Jayasing, Chitta Ranjan Sarangi, Mihir K Mohapatra

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i12.21

Abstract

Background: Gastrointestinal stromal tumor (GIST) is the commonest mesenchymal tumor of gastrointes-tinal tract. Gastrointestinal bleeding, obstruction, pain and abdominal lump are the common clinical manifestations. Local or segmental resection provides satisfactory results.

Methods: Between January 2010 and November 2017, we performed surgery for 14 cases of GIST

Results: Resection was completed in 13 cases. In one case definitive surgery was abandoned due to local invasion and metastasis.

Conclusion: Non-radical surgery in the form of local or segmental resection is the standard surgical approach for GIST management. Recurrence rate is low and long term survival is satisfactory.

Keywords: Gastrointestinal stromal tumor (GIST), Immuno-histochemistry (IHC), CD117.

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