Sole Epidural anaesthesia is suitable for massive Spleenomegaly as it has definite advantages over General anaesthesia. The segmental sole Epidural block denotes the use of a segmental blocked involved in field of surgery and also avoids haemodynamic changes in comorbids conditions.

Keywords: Hereditary Spherocytosis, Segmental Epidural Anaesthesia, Spleenomegaly, General Anaesthesia.

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