Title: Serum Magnesium Level as a Predictor of Micro and Macro Vascular Complications of Type 2 Diabetes Mellitus

Authors: Dr Makkhan Lal Saini, Dr Ravi Dutt, Dr Sangeeta Gahlot

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i10.160

Abstract

Background: Diabetes mellitus promote to impaired metabolism of carbohydrates, proteins, fats, water and electrolytes. Micronutrient have been explore as a potential, preventive and therapeutic agents for type 2 diabetes mellitus and their complications. Hence, this study was planned to evaluate the serum magnesium levels in patients with type 2 DM and to correlate them with the microvascular complications.

Material & Methods: A cross sectional study was done, in which subjects with DM type 2 attending medicine OPD and admitted in S.P. Medical College, Bikaner were taken as cases also of age group above 30 years. A total of 150 patients with type 2 diabetes mellitus were included in the study.

Results: This is a hospital based cross sectional study observed that majority of patients were male (71.33%) and female were (28.67%). The serum magnesium levels were between 1.8 to 2.5 mg/dL (normomagnesemia) among 58.67% of the patients while 41.33% of the patients had serum magnesium levels of < 1.8 mg/dL (hypomagnesemia) and hypomagnesemia (< 1.8 mg/dL) is seen in 58.54% of the patients with microvascular complications compared to 20.59% of the patients. This difference was statistically significant (p<0.001).

Conclusion: Hypomagnesemia is widely prevalent (41.33%) among patients with type 2 diabetes mellitus and lower serum magnesium was seen in patients with poor control and longer duration of diabetes.

Keywords: Diabetes mellitus, Serum magnesium, Microvascular complication.

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