Title: Intra Operative Cytological Examination as a Diagnostic Tool for Carcinoma Breast Comparing With Frozen Section

Authors: Dr A Sarath Kumar, Dr Jisha K T

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i9.87

Abstract

Introduction: Intra operative cytology and frozen section in carcinoma breast 

Materials and Method: FNAC proven surgical specimens of breast malignancies form the Department of surgery during the period 3years. Total of 200 cases with relevant clinical details, gross morphological features of the lesions were observed and recorded. Then specimens for cytological examination and frozen section study were collected, from the suspected focus of malignancy such as infiltrative and irregular gray white areas. Nuclear grading was done on cytological smears. Cytology smears compared with frozen sections.  Study was approved by the institutional ethical committee.                  

Result: Gross examination and intra operative cytology together gave an accuracy rate of 100% in malignant breast lesions. With frozen section alone, the accuracy rate was 96%. 

Conclusion: Intra operative cytology adds confidence to frozen section study.  Intra Operative consultation by cytological examination was an easy procedure to perform  and requires less time compared to frozen section and is of great  value in areas where frozen section facility not available.

Keywords: Intra operative cytology, frozen section, breast malignancy.

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