Background: Human immunodeficiency virus (HIV) is the leading cause of mortality among patients with Tuberculosis (TB) and the majority of them occur in developing countries. The aim of study is to find the prevalence of HIV status among TB patients in PCMC area.

Materials and Methods: The type of study was observational cross sectional study. Total 150 subjects were taken in this study. The study was conducted at the City Tuberculosis Center, Pimpri Chinchwad Municipal Corporation, Pimpri, Pune, over a period of 10 months. Subjects were taken from City TB Center, Pimpri Chinchwad Municipal Corporation, Pimpri, Pune, diagnosis was made by Serology for HIV.

Results: The study showed that Mean age of HIV negative was found to be 33.15, whereas HIV positive was 40.17. Frequency of HIV in TB patients was 6 out of 150 cases. Gender wise HIV negative males were 95.06%, whereas females were 97.1%, as compared to HIV positive males were 4.94%, as compared to females were 2.9%. Residential status of HIV negative was 95.51% in slum & 96.72% in urban, whereas in HIV positive 4.49% in slum & 3.28% in urban area. Treatment Category-I of TB in HIV negative was 97.03% & in Category II was 93.88%, whereas in HIV positive was 2.97% in Category I & 6.12% in Category II. There was a significant (p<0.05) correlation between Tuberculosis infection & HIV.

Conclusion: The prevalence of HIV/TB co-infection in our study was found to be 4%.

Keywords: HIV, Tuberculosis, Serology for HIV.

1. P. Park's Textbook of Preventive and Social Medicine.20^th ed.Jabalpur (India): BanarsidasBhanot 2009. P. 159. 25/6/2014].
2. Journal BM. Medical Research Council. Treatment of pulmonary tuberculosis with streptomycin and para-aminosalicylic acid. BMJ 1950; 2: 1073–1085. British Medical Journal. 1950.
3. Ellard G. The potential clinical significance of the isoniazid acetylator phenotype in the treatment of pulmonary tuberculosis. Tubercle. 1984;65(3):211-27.
4. Vareldzis BP, Grosset J, De Kantor I, Crofton J, Laszlo A, Felten M, et al. Drug-resistant tuberculosis: laboratory issues: World Health Organization recommendations. Tubercle and Lung Disease. 1994;75(1):1-7.
5. Fox W, Ellard GA, Mitchison DA. Studies on the treatment of tuberculosis undertaken by the British Medical Research Council tuberculosis units, 1946–1986, with relevant subsequent publications. The International Journal of Tuberculosis and Lung Disease. 1999;3(10s2):S231-S79.
6. Frieden TR, Sterling T, Pablos-Mendez A, Kilburn JO, Cauthen GM, Dooley SW. The emergence of drug-resistant tuberculosis in New York City. New England journal of medicine. 1993;328(8):521-6.
7. Loddenkemper R, Sagebiel D, Brendel A. Strategies against multidrug-resistant tuberculosis. European Respiratory Journal. 2002;20(36 suppl):66s-77s.
8. Loddenkemper R, Hauer B. Drug-resistant tuberculosis: a worldwide epidemic poses a new challenge. DtschArztebl Int. 2010;107(1-2):10-9. Epub 2010/01/22.
9. P F. The major infectious diseases in the world--to treat or not to treat? N Engl J. Med July 2001;345(3):208-10(july 2001).
10. Shenoi S, Friedland G. Extensively drug-resistant tuberculosis: a new face to an old pathogen. Annual review of medicine. 2009;60:307.
11. Mukesela A. Prevalence of Multidrug-Resistant Tuberculosis in Adults at University Teaching Hospital. 2011.
12. Eriki P.P., Okwera A. and Aisu T. : The influence of human immunodeficiency virus infection on tuberculosis in Kampala, Uganda. Am Rev Respir Dis. 1991.42, 128
13. M. LuoN. andTemboG.: Impact of HIV on tuberculosis in Zambia : a cross-sectional study, fir Med.I. 1990, 301, 412
14. Onorato I.M. and McCray E. : Prevalence of Human Immunodeficiency Virus infec-tion among patients attending tuberculosis clinics in the United States. Journal of Infectious Diseases. 1992, 165, 87
15. Solomon S. Kumarasvvamy N., Anuradhu S.. Vennila R. and Pal JaykarS.A.: Tuberculosis and HIV infection - an association, Indian J Med Microbiol. 1994, 12(4), 313
16. Banavaliker J.N., Gupta R., Sharma D.C., Goel M.K. and Kumari S. : HIV seropositivity in hospitalized pulmonary tuberculosis patients in Delhi. Ind J Tub. 1997, 44, 17
17. Jayaswal R., Arora P.N. and Panda B.N. : HIV in tuberculosis, Medical Journal Armed Forces. India 1995, 51, 259
18. Joint United Nations programme on HIV/AIDS and WHO 2002. AIDS epidemic update December 2002. UN AIDS 102. 58 E Geneva; UNAIDS;2002.

Saumitra S. Sinha

Department of Community Medicine, Dr. D. Y.Patil Medical College, Hospital and Research Centre,

Dr. D. Y. Patil Vidyapeeth, Pune, Maharashtra, India