Title: Seizure type and interictal epileptiform EEG patterns in Nigerians
Authors: Osalusi, B S, Idowu OE, Ogun SA, Ogunsemi OO, Adeeko OO
DOI: https://dx.doi.org/10.18535/jmscr/v5i8.142
Abstract
Introduction: The purpose of this study was to define and establish the relationship of clinically diagnosed seizures with electroencephalographic (EEG) pattern and to determine the effective role of EEG in diagnosis of patients suffering from epileptic seizures.
Methods: We reviewed the charts of 615 patients with seizure disorder who had an electroencephalography performed between over three years. The data using EEG-findings was broken into the following nine study groups: I) normal, II) Generalized Slowing, III) Generalized Sharp and Slow waves, IV) Generalized Sharp and Slow waves with focal spikes, V) Focal Spikes, VI) focal sharp and slow waves, VII) Focal Slow waves, VIII) Generalized spike and IX)Generalized slow waves plus focal sharp waves. The role of EEGs in the diagnosis of seizures was evaluated by comparing the Clinical Neurological pattern of the cases with their EEG-findings.
Results: A total of 615 patients with male to female ratio of 1.5:1. Generalized tonic-clonic seizures were the most common type of seizures (47.6%), followed by partial seizures with secondary generalization (34.9%). Nocturnal seizures was present in 3.1% (n=19), absence seizures in 0.2%, myoclonic epilepsy in 0.7% and complex partial seizures in 5.1%. The relationship of various types of seizures with EEG-patterns showed that general concordance rate of 63.3%concordance and 36.7%discordance EEG findings.
Conclusions: That 55.57%patients were finally diagnosed with the EEG re-emphasizes its importance in the final diagnosis especially in classification of seizures.
Keywords: EEG-pattern; Epilepsy; Seizures.
References
- World Health Organization. Epilepsy Fact Sheet N°999. 2012. Available at: http://www.who.int/mediacentre/factsheets/fs999/en/index.html
- Osuntokun BO, et al. Prevalence of the epilepsies in Nigerian Africans: A community-based study. 1987;28:272–9.
- Danesi MA, Oni K. Profile of epilepsy in Lagos, Nigeria. Trop Geogr Med. 1983;35:9–13.
- World Health Organization, author.Atlas: epilepsy care in the world. Geneva: WHO; 2005.
- Kutsy, R.L. 1999. Focus Extra Temporal Epilepsy: Clinical Features, EEG Patterns, and Surgical Approach. Neurol Sci. 166(1):1-15.
- Senanayake N. 1993 .Classification of epileptic seizures: a hospital-based study of 1,250 patients in a developing country. Epilepsia(34)812–818
- Kabiraj, M.M, et al. 2003. EEG-Pattern in Patients with Complex Partial Seizures. GJST.3(2):152-158.
- Jerger, K.K., et al. 2001. Early Seizure Detection. Clin Neurophysiol.18(3):259-68.
- Matinez, M.B., et al. 2000, Generalized Spike and Wave Patterns in Children: Clinical Correlates. Pediatr Neurol.22 (1):23-8.
- Hammer, H.M., et al. 1999. Symptoma-tology of Epileptic Seizures in the First Three Years of Life. Epilepsia.40(7):837-44.
- Nowack, W.J., et al. 2002. Clinical Correlate of EEG Rhythmcity. J ClinNeurophysol.19(1):32-6.
- Watanbe, K. and A. Okumura. 2000. BenignPartial Epilepsies in Infancy. Brain Dev.22(5):296-300
- Bauzanao, P.E, and B.A.C. Rodriguez. 2001. Electroencephalographic Diagnosis of Idiopathic Generalized Epilepsies of Childhood. RevNeurol.32(4):365-72.
- Massa, R., et al. 2001. EEG Criteria Predictive of Complicated Evolution in Idiopathic Rolandic Epilepsy. Neurology.57(6):1071-9.
- Gosavi TD, et al.2015 Ictal and interictal EEG patterns in patients with nonconvulsive and subtle convulsive status epilepticus; Epilepsy Behav. (49):263-7
- Owolabi L, etal 2014Clinico-Electroencephalography Pattern and Determinant of 2-year Seizure Control in Patients with Complex Partial Seizure Disorder in Kano, Northwestern Nigeria. Ann Med Health Sci Res. (2):186-91.
- Al-Suleman, A.A, 2001. Epilepsy in Saudi Children with Cerebral Palsy. Saudi Med J. 22(1):19-21
- Niedzielska, K., et al. 1997. Differential Diagnosis in Idiopathic Generalized Epilepsies with Tonic-Clonic Seizures: Assessment of the use of Ambulatory EEG and Video/EEG Monitoring. Neural Neurochir Pol.31(2):217-27.
- Stanley C. et al 2014 Patterns of diagnosis and therapeutic care of epilepsy at a tertiary referral center in Nigeria. Epilepsia vol 55 (3)442-447.