Aim: To determine the prevalence of metaplasia and dysplasia among south Indian patients undergoing  cholecystectomy.

Materials and Methods: Patients undergoing laparoscopic/ open cholecystectomy from January 2015 to December 2016 were included.  Retrospective data on age, sex, residence and presence of common bile duct stones was collected.  Peri operative information included colour of gallstones and histopathology of the gallbladder. 

Results: 235 gallbladder specimens (115 males) with median age of 49.3 years (17-83 years) were studied. Chronic cholecystitis was the commonest pathological finding followed by acute on chronic cholecystitis, acute cholecystitis and acute necrotising cholecystitis respectively.  Six specimens (2.5%) showed an antral metaplasia and one each (0.4%) had focal micropapillary changes and low grade dysplasia. 

Conclusion: Gallstone related cholecystitis in south India is often chronic and affects men and women equally. Chronic cholecystitis though the commonest pathological type was not associated with metaplasia or gallbladder cancer. 

Keywords: gall bladder, premaliganat, India, mucosa.

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Mayank Jain

Gleneagles Global Health City Chennai-100

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