Title: Non-Hodgkin’s Lymphoma: A Clinical autopsy case report with review of literature

Authors: Dr M A Sameer, Dr Rohit Mangal

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i8.78

Abstract

We report a clinical autopsy case in a 32 year-old female who was admitted to our hospital in pulmonary medicine with chief complaints of breathlessness dyspnea, fever since 1 month and clinically diagnosed as pulmonary tuberculosis (PTB) defaulter. Ultrasonography (USG) revealed mild hepatomegaly with fatty changes.Patient died on third day of treatment, so her autopsy was performed. The findings of autopsy examination was pale and congested lungs at places, kidney, small and large intestine, liver, uterus bilateral adnexa, shows multiple white nodule of size 0.5X0.5cm.The wall of large intestine was thickened and multiple patches of 5cm were noted. Also we found congested spleen and mild spleenomegaly. Brain and heart was unremarkable. Histopathology examination showed non Hodgkin’s lymphoma with bilateral infiltration of tumor in lung, liver, kidneys, intestine, ovaries and fallopian tubes. Most commonly primary may be the large intestine.There was no effect on any foci of PTB on p.m. examination or in histopathology.

Keywords: Autopsy, Pulmonary tuberculosis (PTB), Ultrasonography (USG), Histopathology, Immunohistochemistry (IHC), Non Hodgkin’s Lymphoma.

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