Title: A Clinico Etiological Study of Cutaneous Drug Eruptions
Authors: Dr M. Nithya Kumari M.D., Dr K.Sridevi, M.D., Associate Professor, Dr G.Ramesh Kumar, Professor
DOI: https://dx.doi.org/10.18535/jmscr/v5i7.243
Abstract
Background: To study the clinical spectrum of Cutaneous adverse drug reactions (ACDRS) in hospitalized patients and to establish a causal link between the drug and the reaction by using WHO causality definitions.
Objectives:
- To calculate prevalence of ACDRS
- To evaluate various etiological factors
- To study clinical patterns
Methods: All patients attending to the OPD and IPD of D.V.L. and patients referred from other departments with suspected ACDRs were included in the study.
Results: In the present study most common offending drug group is antimicrobials (48.6%) followed by 20% of anticonvulsants, 12.8% cases of NSAIDS and 18.6% others. Common morphological types of ACDRs were acneiform eruptions, F.D.E, maculopapular rash, TEN-SJS, Dapsone syndrome and Pruritis.
Keywords: Adverse Cutaneous drug reactions- Etiology- Drug eruptions
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