The aim of present Electroencephalography (EEG) study was to investigate the role of absolute power to discriminate Alzheimer’s disease patient and normal elderly subjects. EEG was recorded at rest in age-sex matched 30 normal elderly subjects and 20 amnesic Alzheimer’s disease patients (55-75 years) for Mini Mental State Examination. The EEG bands so evaluated were delta (0.2-3.9 Hz), theta (4.0-7.9 Hz), alpha (8.1- 12.9 Hz), beta (13.0 -30.0 Hz) and gamma (30.1-80 Hz). A significant decrease MMSE score was observed in patients when compared to controls (p=0.000). Amnesic Alzheimer’s patients showed significant (p=0.001) increased delta absolute power in fronto-central and parieto-occipital region of the brain. Theta bands tended to increased (p=0.000) absolute power in parieto-occipital region in Amnesic Alzheimer’s patients. Significant decreased (p=0.000) alpha, beta and gamma absolute power were observed in both fronto-central and parieto-occipital region of the brain in Amnesic Alzheimer’s patients. These results suggest that absolute power can discriminate Amnesic Alzheimer’s patients from normal elderly subjects.

Keywords: Amnesic Alzheimer’s patients, Electroencephalography (EEG), Mini Mental State Examination

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Sweta Soni

Department of Physiology, S.M.S. Medical College, Jaipur (Rajasthan) India

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