Title: Study of Etiology and Clinical Assessment of Crescentic Glomerulonephritis
Authors: Dr Roopak Kumar, Dr Rajeev Krishna Choudhary
DOI: https://dx.doi.org/10.18535/jmscr/v5i7.185
Abstract
Rapidly progressive glomerulonephritis (RPGN) is a condition of the kidney that is considered by a rapid loss of renal function. The study had prearranged with the purpose to designate the etiological profile and clinical course in patients with crescentic GN. The study was attended in the Indira Gandhi Institute of Medical Sciences, Patna for the period of the 1year in the patients identified with the crescentic glomerulonephritis. The clinical, biochemical and histopathological constraints and primary consequences were allied between immune-complex glomerulonephritis (ICGN) and pauci-immune glomerulonephritis (PauciGN).
The total number of glomeruli, crescents, Fibrocellular crescents, Tubular atrophy, Interstitial fibrosis are comprehended more in immune-complex glomerulonephritis. The Hypertension is perceived in the both the glomerulonephritis conditions. Edema is seen more in the PauciGN than in ICGN group. There is for emostalteration in the urine output in ICGN and PauciGN. Total 77% of the Immune-complex glomerulonephritis cases were observed. 27% of the cases also showed the IgA nephropathy as a major cause of the crescentic glomerulonephritis. Lupus nephritis is found in 20% of the study group.
From the above study as well as the already published literature it can be determined that Immune-complex glomerulonephritis is the most communal reason of Crescentic Glomerulonephritis in the selected study group patients with IgA nephropathy existence the principal disease.
Keyword: Crescentic glomerulonephritis, immune-complex glomerulonephritis, pauci-immume glomerulonephritis.
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