Title: Comparison of Fine Needle Aspiration versus Non-Aspiration Cytology in Diagnosis of Non-Neoplastic Thyroid Lesions
Authors: Bhavneet Kour, Pankaj Singh, Gagandeep Singh
DOI: https://dx.doi.org/10.18535/jmscr/v5i7.157
Abstract
Background: Preoperative evaluation of thyroid disorder is mandatory for proper management of the patient so as to avoid unnecessary surgery. Fine needle aspiration cytology is the first line diagnostic test for evaluation of goitre and single most effective test for preoperative diagnosis of solitary thyroid nodule. Fine needle non-aspiration cytology avoids aspiration but permits cytologic diagnosis of the thyroid masses.
Aim of the study: To compare the results of Fine Needle Aspiration Cytology (FNAC) and Fine Needle Non Aspiration Cytology (FNNAC) in diagnosis of non-neoplastic thyroid lesions.
Materials and Methods: One-year observational study, conducted on 125 patients with non-neoplastic thyroid lesions in a tertiary care centre of north India. Patients were investigated with a thyroid function test and a needle biopsy. Both FNAC and FNNAC techniques were performed simultaneously at the same site by the same investigator Modified scoring system was employed to categorise each specimen.
Results: A total of 125 patients with non-neoplastic thyroid lesions were subjected to needle biopsies both aspirated and non-aspirated simultaneously. Females dominated the study with female to male ratio of 5.25:1. Colloid goiter was observed in 50.40% female and in7.20% male patients. Thyroiditis was observed in 30.40% female and in 3.20% male patients. Thyroglossal cyst was observed in 4.80% male and in 0.80% female patients, while colloid cyst was observed in 2.40% female and 0.80% male patients. Most of the non-neoplastic thyroid lesions (31.20%) were observed in the age group of 31-40 years. More lesions were observed as diagnostically adequate by FNAC, while diagnostically superior lesions were more in case of FNNAC
Conclusion: FNAC smears produced more adequate results, while. FNNAC was more diagnostically superior. Both the techniques were suitable for preoperative diagnosis of non-neoplastic thyroid lesions.
Keywords: Thyroid lesions, Non-neoplastic, Fine needle aspiration, Fine needle non-aspiration, Cytology.
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