Title: Correlation of Maternal Factors on Neonatal Jaundice
Authors: Sapnadevi Dasian Pankajakshy, Deepa Mohandas, Rinku Girija, Sobhana P
DOI: https://dx.doi.org/10.18535/jmscr/v5i7.80
Abstract
Background: Neonatal jaundice is a common problem affecting the newborn. About 25-50% of term newborn and higher percentage of premature newborn develop clinical jaundice and serum bilirubin >15mg/dl is seen in 3% normal term babies.
Materials and Methods: This is an observational case control study of 250 randomly selected pregnant women who delivered at SAT Hospital, Medical College, Thiruvavananthapuram. They were followed up for one week in the postnatal ward following delivery and babies were observed for the development of jaundice.
Results: 73 babies developed neonatal jaundice and were considered as group I or cases. 177 babies did not develop NNJ, taken as group II and were considered as controls. The significant risk factors associated with NNJ in the present study were history of abortion and NNJ in previous pregnancy, Prematurity, ABO incompatibility, Rh incompatibility, Oxytocin use, PROM / PPROM, instrumental deliveries, birth asphyxia and sepsis.
Conclusion: Neonatal jaundice is a major causeof neonatal morbidity and NICU admission. Hence all efforts should be made to identify the preventable causes of neonatal jaundice.
References
1. Burke. BL, Robnbins JM et al: Trends in hospitalization for neonatal jaundice and Kernicterus in the U.S. Pediatrics 123 (2); 524, 2009.
2. Dijik.DH, HJulzehos C: An evidence based view on hyperbilirubinemia. Acta Pediatric suppl. 161 (464) : 3, 2012.
3. Kaplan M, Bromiker R: Severe neonatal hyperbilirubinemia and kernicterus; are these still problems in the third millen-nium? Neonatalogy 100 (4): 354, 2011.
4. Hansen TWR: Prevention of neurodevelopmental sequelae of jaundice in the newborn. Dev. Med. Child. Neurol 53 (suppl 4): 24, 2011.
5. Fretts R C, Boyde M E, Usher R H: The changing pattern of fetal death, 1961 - 1988. Obstet .Gynaecol 1992; 79: 35.
6. Oski F A, 1982. Anemia in the neonatal period. In hematological problems in the newborn. Eds F A Oski , L Naiman, W B Saunders, Philadelphia, p.55.
7. Chalmers I , Campbell H, Turnbull AC. Use of oxytocin and incidence of neonatal jaundice. Br..Med J. 1975 April 19; 2 (5963) : 116 - 8.
8. ACOG: Management of alloimmunization during pregnancy. Practice bulletin No.75, Aug 2006. Reaffirmed 2012.
9. Canlorde G, Cortey A etal: Mangement of very early fetal anemia resulting from red cell allo- immunization before 20 weeks of gestation obstet Gynecol 118 (6):1323, 2011.
10. Arad I, Fainmesser P, Birkinfeld A, Gulaiev B: •Vacuum extraction and neonatal jaundice . J. Perin Med 1982; 10(6) : 273-8.
11. Jahrig D, Jahrig K, Stiete S, Beyersdorff Poser H, Hopp H Neonatal jaundice in infants of diabetic mothers. Acta Paediatr Scand suppl- 1989; 360: 101-7.
12. Gale R, Seidman D S, Dollberg S, Stevenson DK : Epidemiology of neonatal jaundice in Jerusalem Population. J Paed Gastroenterol Nute 1990 Jan; 10 (1) : 82-6.
13. Hier HE, Feigelselk D, Lindemann R, Quigstad E; Maternal blood group 0 as a risk factor for neonatal hyperbilirubinemia requiring treatment. Tiddsker Nor Laegeforen. 1996 Jan; 116(1):34-36.
14. Gupte SC, Kulkarni S.S. Incidence of Rh isoimmunisation between 1981 and 1992. Natl. Med J. India. 1994; 7: 65-66.