Title: Risk Factors for Twinning with Special Reference to Chorionicity – A Hospital Based Study

Authors: Lekshmi Murukesan, Mayadevi Brahmanandan, Sujamol Jacob

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i6.200

Abstract

Background: The rise in the incidence of twin pregnancies all over the world is not only due to assisted reproductive techniques but also due to various other risk factors. Twin pregnancy is associated with increased risk of maternal and fetal complications which in turn increases financial, emotional and social cost to the twins themselves and their families.

Materials and Methods: A clinical non-interventional ‘nested’ case control study was conducted in a tertiary care centre over a period of 1 year. To study the risk factors, all the required data were collected by personal interview of mothers.

Results: Nearly one third of twins were monochorionic twins. Dichorionic twins were found to be more in higher socio-economic groups, maternal age > 25 years, advanced parity and infertility treatment, especially ovulation induction with clomiphene citrate.

Conclusions: Epidemiological studies on twins helps us in better understanding the phenomenon of childbirth.

Key Words: Chorionicity, Monochorionic, Dichorionic, Twins.

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