Title: Comparative Study of Plain Bupivacaine and Bupivacaine with Clonidine for Caudal Epidural in Paediatric Patients
Authors: Dr Shweta Mehta, Dr Jigisha Makwana
DOI: https://dx.doi.org/10.18535/jmscr/v5i6.72
Abstract
Aims and Objectives: To compare perioperative haemodynamic changes and complications, the quality and duration of post operative analgesia, total number of rescue analgesic doses required and degree and duration of sedation post operatively in each group.
Material and Method:70 children of ASA grade I or II aged 5-10 years, undergoing elective infraumbilical surgies were randomly allocated to group A(n=35)(0.25% plain bupivacaine 1 ml/kg+1 ml normal saline) and group B(n=35)(0.25% bupivacaine 1 ml/kg + clonidine 1mcg/kg in 1 ml normal saline). Post operative pain scores, duration of analgesia, total number of rescue analgesic doses required, haemodynamic changes, perioperative complications and degree and duration of sedation were recorded. Pain score was assessed using OPS score,
Results: The mean duration of analgesia in postoperative period was more in group B(9.20 ±0.76) hours as compared to Group A (4.9 ± 1.23) hours ;P<0.05.The children in group B had lower pain scores as compared to group A which was statistically significant. 100% patients in group A required two or more than two doses of rescue analgesic whereas in group B 85% patients required single dose of rescue analgesic and 12% patients required two doses of rescue analgesic in first 12 hours post operatively. Mean sedation scores were higher in group B as compared to group A
Conclusion: Addition of clonidine (1 mcg/kg) to bupicaine (0.25% 1 ml/kg) to caudal epidural block prolongs the duration of analgesia in paediatric patients.
Keyword: Paediatric patients, caudal epidural block, bupicaine and clonidine, postoperative analgesia.
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