Title: Comparative study of Olmesartan and Telmisartan on reduction of raised diastolic blood pressure in patient with age more than 40 years
Author: Dr Amit Kumar Jha
DOI: https://dx.doi.org/10.18535/jmscr/v5i6.33
Abstract
Hypertension is a major risk factor for cardiovascular morbidity and mortality. Antihypertensive drug is used to reduce blood pressure. In addition, angiotensin receptor blocker has shown beneficial effect for controlling target organ damage. Furthermore unlike ACE inhibitor these agents have side effect profile that is similar to that of placebo. Study was carried out for production of hypertension by psychogenic stress method. In present work done by me antihypertensive effect of olmesartan and telmisartan was compared with control and with each other .student t-test was done to compare result. It was found that blood pressure varied significantly across the three groups (P=.000).compared to control group, blood pressure was significantly less in both olmesartan and telmisartan (p=.000). Reduction of blood pressure with olmesartan was more than with telmisartan at the end of work. Olmesartan is more efficacious than telmisartan as far as blood pressure reduction is concerned.
Keyword: olmesartan, telmisartan, Antihypertensive effect.
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