Title: Clinical Profile and Spectrum of Complications of Diabetes at the Onset of Younger Age

Authors: Jayanta Kumar Panda, Manjushree Nayak, Deepak Ramchandran, Sunil Gupta, Jothydev Kesavadev

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i5.234

Abstract

 Introduction: The incidence with younger patients is continuously growing in the regular clinical care setting. Unhealthy lifestyle, sedentary habits are responsible for the changing dynamics of diabetes in young

Objectives: To evaluate the incidence, clinical profile and spectrum of complications of different types of diabetes mellitus among young patients (age between 15 to 25 years).

Materials and Methods: Cross-sectional study of every consecutive diabetic patient of age of onset between 15 to 25 years attending Department of Medicine and department of Endocrinology

Results: We studies 60 patients of which Type 1 DM accounted for the highest no. of cases (61%). In Type 1 DM males (85%) were more affected and in Type 2 DM males and females were equally affected. Osmotic symptoms were present predominantly in Type 1 DM (67%). Positive family history was highest in Type 2 DM (81.2%) cases.  Retinopathy was present in 28% of the total cases of young diabetes, predominantly in Type 2 DM (43.7%). Nephropathy is present in 16.6% of the cases of diabetes, in general predominating in  Type 1 DM(22%). Both autonomic and peripheral neuropathy were found to be highest in Type 2 DM .

Conclusions: This group represents an extreme phenotype with high prevalence of risk factors. Hence, a study on diabetes in young is very much relevant in the present scenario.

Keywords: Diabetes mellitus, Fasting plasma glucose,Type1 diabetes mellitus, Type 2 diabetes mellitus, Fibrocalculus pancreatic diabetes, Maturity Onset Diabetes of Young,neuropathy ,nephropathy,retinopathy.

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