Objective: To Study the Clinical Profile and Etiology of Partial seizures in Adults at Tertiary care centre.

Method: In this Descriptive, cross sectional study, a total of 135 patients were selected over 1 year. All patients with partial seizures in adulthood were included. Patient below the age of 18 years, seizure type other than partial seizures, Pseudo seizures and patients with history of seizure before the age of 18 years were excluded. Data was entered and analyzed on SPSS software.

Results: Maximum number of cases were due to Neurocysticercosis (NCC) (36.30%). Maximum showed simple partial seizure (45.19%), followed by complex partial seizure (33.33%) and complex partial seizures with secondary generalization (21.48%). Of the 135 cases of partial seizures 100 (74.07%) were males and 35 (25.93%) were females with male to female ratio of 2.8:1. Maximum cases were in the age group of 18 -30 years (males = 20.74% and females = 31.85%). Common symptoms of patient during partial seizures were frothing from mouth (60%), headache (52.59%), aura (51.85%) and uprolling of eye balls (43.73%).Symptoms of patients in postictal phase were headache (62.22%), post ictal confusion (55.56%) and focal deficit (26.67%). Family history was present in 6.67%.Cases of trauma (2.22%) were diagnosed on non contrast computed tomography (NCCT)  head. 7.78% of NCC were picked up on NCCT head. Infection (0.74%), mesial temporal lobe epilepsy (MTLE) (0.74%), posterior reversible encephalopathy syndrome (PRES) (0.74%), tumor (3%) were all diagnosed on magnetic resonance imaging (MRI).Electroencephalogram (EEG) was done in 69 (51.11%) cases and 49.28% were abnormal.

Conclusion: NCC still account for a significant number of cases. Males are more prone to partial seizures in our region with more episodes seen in younger age. Every case of partial seizures must be evaluated with EEG and radiological scan – either MRI brain, CECT brain or NCCT brain.

Key Words- Simple partial seizure (SPS), Complex partial seizure (CPS), Neurocysticercosis (NCC), Mesial temporal lobe epilepsy (MTLE), Posterior reversible encephalopathy syndrome (PRES), Cerebral calcified CT lesion (CCCTL).

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Chaudhry Aditya

Senior Resident, Department of Medicine,

Himalayan Institute of Medical Sciences, Swami Rama Himalayan University,

Dehradun-248140, Uttarakhand, India