Title: Evaluation of Cardiovascular Status in Thyroid Disorders
Authors: Dr Subodh Banzal, Dr Abhishek Singhai, Dr Nikhil Bakhtar, Dr Sourabh Singh Dudve, Dr Rajesh Kumar Jha
DOI: https://dx.doi.org/10.18535/jmscr/v5i5.180
Abstract
Context: Thyroid disorders (hypothyroidism and hyperthyroidism) are associated with clinically significant cardiovascular changes. In the present study, patients with various types of thyroid disorders examined clinically and biochemically. Their cardiovascular status assessed by electrocardiography, radiologically and echocardiographically, and compared with controls with an aim to determine the effect of thyroid disease on the cardiac status.
Methods and Material: This is a case control study, conducted at a tertiary care centre for two years. This study included 80 cases, comprised of 40 cases of hyperthyroidism and 40 cases of hypothyroidism. 40 healthy age and sex matched subjects were also included in the study as a control for comparison.
Statistical analysis used: Pearson’s Chi-Square test was used for qualitative data to observe the association of the thyroid diseases with cardiovascular abnormalities in hyperthyroid, hypothyroid patients and controls subjects.
Results: Among hyperthyroid patients, sinus tachycardia was the predominant ECG abnormality while, sinus bradycardia was the most common findings among hypothyroid cases. Diastolic dysfunction was seen in 10% of hyperthyroid subjects and 5% of hypothyroid subjects. Systolic dysfunction was seen in 14% of hyperthyroid subjects and 17% of hypothyroid subjects. Interventricular septum thickness was increased in 17.5% of hypothyroid cases in our study. Serum cholesterol and triglycerides levels were significantly higher in hypothyroidism subjects.
Conclusions: The cardiovascular signs and symptoms of thyroid disease are some of the most profound and clinically relevant findings that accompany both hyperthyroidism and hypothyroidism. Echocardiography is a very valuable tool in evaluation of the effects of hypothyroidism on heart and can detect earliest changes.
Key-words: Hypothyroidism, hyperthyroidism, echocardiography.
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