Title: Study of Clinico Hematological Profile and Outcome of Malaria in Adult Patients Admitted in Hamidia
Authors: Dr Ashish Awaya, Dr R. S. Jagat, Dr T. N. Dubey, Dr Nitin Nahar
DOI: https://dx.doi.org/10.18535/jmscr/v5i5.157
Abstract
Aim: to Study of Clinico Hematological Profile and Outcome of Malaria in Adult Patients Admitted in Hamidia’
Material & Method: The present study was done in department of medicine, GMC & H. H. Bhopal (MP). In this study 100 patients of Malaria confirmed by peripheral smear or by rapid optimal test underwent detailed clinical history through physical examination and investigated with hematologic and coagulation parameters. Patients with established diagnosis of systemic infection, typhoid fever, dengue fever, pulmonary tuberculosis, HIV-AIDS, and Meningitis were excluded from study.
Result: 100 patients who had positive for Malaria infection by peripheral smear or by rapid optimal test were included in this study. Out of these 100 patients 50% of P. Falciparum, 43% patients of P. Vivax & 7% patients of mixed infection. Of the 100 patients, fever (100%) was the most commonest presenting symptoms followed by chills and Rigors(77%), 1% patients had severe Anaemia (hb < 5 gm%), 78% patients had moderate Anaemia(5-10gm%). Thrombocytopenia was observed in 66% patients and out of this severe thrombocytopenia (<50000 cumn) was seen in 3% of patients. PT was increased in 12% and S. Billirubin was increased in 5%. Splenomegaly in 17% and hepatomegaly in 7%. The most common system involved in these study was Hematologic system (79%) followed by renal (19%), Hepatic (7%), neurological (3%) and pulmonary system (2%).
Conclusion: In this study conclude P. Falciparum Malaria is major challenge and usually presents with involvement of almost all system of body. Therefore, it is vital to know & perform hematologic and biochemical investigation to detect early complications and to treat them effectively
Keywords: Malaria, Thrombocyopenia, Anaemia, Leucocytosis, leucopenia.
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