Title: Clinico-pathological profile of Bone Metastases - A Single Institutional Study

Authors: Padhi Sanjukta, Meher Papuji, Sahoo Bijayalaxmi, Patra Jitendra, Mahapatra Bikash Ranjan

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i5.90

Abstract

Background: Cancer of head and neck, prostate and, lungs in males, cancer breast, cervix in females are the most common malignancies in India. These are also the leading cause of death. Patients often present with painful bone metastases. It is of a major concern to patients as well as oncologists.

Aim: To study different primary cancers giving rise to bone metastases. Age distribution, clinical profile, sites, patterns, & distribution of occurrence, diagnostic methods, modes of management given are taken into account.

Materials: The treatment records of 227 patients of bone metastases undergoing palliative radiotherapy treatment at AHRCC. From January 2015 to December 2016 were retrieved and analysed retrospectively.

Results: Majority of patients were from 4th to 6th decade of life. Cancer prostate followed by lung cancer are most common in males. Breast and gynaecological cancer are common in females.  Spine is the most favoured site followed by pelvis. Rib, long bone and skull metastases were also seen. Most of the patients presented with  bony pain .All were managed with radiotherapy using different fractionation schedules. Few had undergone surgical interventions.

Conclusion: Skeletal metastases if properly managed can give rise to better quality of life. It depends upon the early and accurate diagnosis proper bone health maintenance and management by multidisciplinary team.

Keywords:  Bone Metastases, radiotherapy.

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