Title: A Study of Drug Use in Type 2 Diabetes Mellitus with and Without Co-Morbidities in Patients Visiting A Tertiary Care Hospital
Authors: Dr Vikram N. Patil, Dr Padmakar T. Pandit, Dr Balasaheb B. Ghongane
DOI: https://dx.doi.org/10.18535/jmscr/v5i5.30
Abstract
Background: A good number of diabetes patients suffer from co-morbidities such as hypertension, hyperlipidaemia and ischemic heart disease. Owing to the presence of co-morbid conditions, geriatric patients usually receive more than one drug. Objective of the study is to evaluate the drug use in type 2 diabetes mellitus (DM) with and without co-morbidities in patients visiting a tertiary care hospital.
Methods: Prospective, observational study was carried out at diabetic OPD of B. J. Government Medical College and Sassoon General hospital, Pune, where Consecutive 400 prescriptions from diabetic OPD were positioned into a case record form and antidiabetic drug utilization pattern was analyzed.
Results: In the present study, 43% patients had DM without co-morbidities while 57% patients had co-morbidities. Majority of Type 2 DM was found to be most prevalent in the age group of 61-75 years, with Hypertension was the most prevalent co-morbidity (60.52%). In DM without co-morbidities there were change in anti-diabetic prescription seen in (29.06%) and in DM with co-morbidity there were change in anti-diabetic prescription seen in (25.87%) patients. DM without co-morbidities at 0 day and at 3 months 56.97%, 63.95% prescription had Drug-Drug Interactions (DDIs) and in DM with co-morbidities at 0 day and at 3 months 76.31%, 74.12% prescription had DDIs.
Conclusions: Prescription after 3 months was changed in some patients due to uncontrolled diabetes mellitus. Hypertension was the most common co-morbid condition present while Tablet Metformin was most commonly prescribed drug in diabetes mellitus without co-morbidity and with co-morbidities patients respectively.
Keywords-Anti-diabetic drugs, Co-morbidity, Generic name, Drug interactions.
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