Title: Leukemia Cutis with Acute Myelomonocytic Leukemia Presenting As a Benign Appearing Maculopapular Rash: A Rare and Interesting Case Report

Authors: Dr Kalaivani Amitkumar, Dr Depayan Bishal, Dr Shivasekar Ganapathy, Dr Buvanamhadevi Ramamurthy, Dr Muthu Sudalaimuthu,  Dr Anand C Damodaran

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i5.11

Abstract

A 54 years old male came with the complaints of raised multiple maculopapular lesions involving the forehead and lateral side of the nose. Skin biopsy showed thinning of epidermis and diffuse monomorphic population of infiltrate involving the dermis and subcutis with round nuclei, high NC ratio and scanty cytoplasm. Complete Haemogram showed low haemoglobin (4.3g/dl), leukocytosis (total count: 43,400/microliter) and marked thrombocytopenia (platelets: 36,000/microliter). Peripheral blood picture revealed acute leukemic picture with 45% myeloblasts and 46% of monocytes and its precursors. It was confirmed as Leukemia cutis with acute myelomonocytic leukemia by further bone marrow aspiration study and immunohistochemistry.

Keywords: Leukemia cutis, bone marrow aspiration, Immunohistochemistry.

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