Title: A Relevance Study of Bone Marrow Aspiration and Bone Marrow Biopsy in Haematological and Non Haematological Disorders
Authors: Dr Daleep Kumar Khatik, Dr Deepika Mishra, Dr Mangilal Choudhary
DOI: https://dx.doi.org/10.18535/jmscr/v5i4.184
Abstract
Introduction: Bone marrow examination is an important diagnostic tool for evaluation of various haematological and non haematological disorders. The two most important techniques used for the diagnosis are bone marrow aspiration and bone marrow trephine biopsy which are complementary to each other.
Aims and Objective: To correlate the bone marrow aspiration and bone marrow biopsy finding in haematological and non haematological disorders.
Material and Methods: A total of 150 cases with both bone marrow aspiration and biopsy were included in the study. All the aspirate smears were routinely stained by leishman stain while the trephine biopsy sections were stained by routine Hematoxylin and Eosin stain. All the smears and sections were examined and the findings of BMA and BMB compared to each other.
Results: In the present study out of 150 cases the positive correlation between bone marrow aspirate and trephine biopsy sections was 89.33 % and sensitivity of bone marrow aspiration cytology was 83%.
Conclusion: The study concludes that preparations of aspirate are easy as compare to trephine biopsy. However both these procedure are complementary to each other in majority of the cases. The advantage of both the procedures done together provide us to study the cytomorphology of the cells along with the pattern of distribution of the cells depending on the cases, hence help in making the diagnosis accurately.
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