Title: Study on Aetiological Profile of Neonatal Sepsis in a Tertiary Care Hospital in Eastern India an Original Article
Authors: Niloy Kumar Das, Alakesh Halder, Baisakhi Soren, Saheli Misra
DOI: https://dx.doi.org/10.18535/jmscr/v5i4.168
Abstract
Introduction-Neonatal sepsis is a major cause of neonatal mortality and morbidity. For proper management knowledge of the pattern of etiological agents and their sensitivity pattern is crucial. The aim of this study was to determine the aetiology and their sensitivity of neonatal septicemia cases.
Materials and Method-It was a retrospective survey study. During 1 year period blood samples were sent for culture sensitivity. Samples were drawn from sick neonates or those having risk factors for developing sepsis. Blood culture was performed using BACTEC 9240, isolates were identified by standard techniques and antibiotic susceptibility was performed as per the CLSI guidelines.
Results -Total 147 samples were sent for blood culture,29 (19.7%) came out positive. Escherichia coli was the most common organism causing sepsis. All Gram positive organisms were sensitive to Vancomycin where for Gram-negative organisms, Colistin and Meropenem mostly effective.
Conclusion- Gram positive organisms were most commonly associated with neonatal sepsis. Commonly used antibiotics like Amoxycillin, Cefotaxime, Amikacin were ineffective to control sepsis
Keywords: neonatal, sepsis,Gram positive,Gram negative organism.
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