Title: Serial Measurement of High Sensitive C Reactive Protein Levels of Patients Having Acute Chest Pain –Study in a Tertiary Care Centre of Western Odisha
Authors: Dr Madhusmita Acharya, Dr Jyotindra Kumar Sahu, Dr Sunil Kumar Sharma, Dr M. K. Mandal
DOI: https://dx.doi.org/10.18535/jmscr/v5i4.81
Abstract
Hscrp as an inflammatory marker has been used as a non invasive method which is significantly increased in patients having chest pain diagnosed to be acute myocardial infarction. Hscrp has been received great attention now a day. According to a number of studies, hscrp concentrations more than 3mg/l is more associated with disease outcome and may worsen the prognosis in patients of acute coronary syndrome. High sensitive c reactive protein levels were measured in150 patients attended to emergency ward of cardiology department of VIMSAR, Burla for chest pain .The mean age group was 50.5 years. AMI was diagnosed in 60 patients. The final diagnosis of chest pain was based on clinical, ECG, echocardiography and two 8hrs apart Troponin I test. AMI was ruled out by negative serial Trop I test. From 60 AMI cases, only 38 cases were having STEMI, and 12 patients were having NSTEMI. 24 patients were suffering from unstable angina. Rest 66 patients were having chest pain of non cardiac origin. Hscrp level in AMI was significantly was higher than in NCCP i.e ().There was no difference between HSCRP level in STEMI and NSTEMI. In this study, patients with chestpain, high levels of HSCRP is associated with AMI, implicating the presence of inflammatory process. A negative HSCRP differential saved performing a number of time consuming processes. This negative HSCRP differential helped as a good screening test in the emergency department to rule out chest pain of cardiac origin and allowing safe discharge.
Keywords: C reactive protein and acute chest pain.
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