Title: Aetiology and Prognosis in Pregnancy Related Acute Renal Failure
Authors: Dr Cicily T J*, Dr Sherin Sams, Dr Bindu K M
DOI: https://dx.doi.org/10.18535/jmscr/v5i3.155
Abstract
Acute renal failure (ARF) is a major complication during pregnancy and is associated with high mortality rate. Acute kidney injury continues to be common in developing countries. We conducted this study to determine the major aetiological factors for pregnancy related acute renal failure (PRARF) in the present setting due to its changing pattern from yester years by detailed study of the clinical profile of obstetric acute renal failure. The study also aims to determine maternal and perinatal outcome in PRARF and prognosis in dialysis instituted patients.
Objectives of the Study
1. To identify the aetiological factors and study the clinical profile of pregnancy related acute renal failure
2. To study the maternal and perinatal outcome in pregnancy related acute renal failure
3. To identify the incidence of dialysis requiring patients in obstetric acute renal failure and its outcome
Materials and Methods
Study design: Prospective study
Study setting: Department of Obstetrics and Gynaecology, Govt. Medical College, Kottayam.
Study period: June 2012 to June 2014
The outcomes of the pregnancies in 50 women who presented with pregnancy related acute renal failure and received their obstetrical care were evaluated, 12 major aetiological factors for development of PRARF were identified. A total of 10 maternal death of PRARF, 22 still births (IUD) and 5 neonatal deaths accounting for 27 perinatal deaths were found. Dialysis was instituted in four patients with PRARF of which three patients expired and only one survived.
Keywords (MeSH): Acute renal failure, Acute Kidney Injury, Pregnancy, Renal Cortical Necrosis
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