Title: HIV/AIDS and Hodgkin’s Lymphoma
Authors: Dr R.Sumathi M.B.B.S., PGDHIVM., C.Dia., Dr M. Vijaya Kumar M.D.
DOI: https://dx.doi.org/10.18535/jmscr/v5i3.148
Abstract
Hodgkin’s disease is noted with increased frequency among HIV infected patients. The decrease of Immunosuppression associated with disease development is variable. Patients usually present late with advanced disease that involves extra nodal sites, most often the bone marrow, the tongue, rectum, skin, heart and lungs might be the sight of involvement. Patients with HIV/AIDS are at increased risk of developing Hodgkin’s lymphoma differ from non HIV infected patient and HL, that it is nearly associated with Epstein Barr Virus, with systemic B Symptoms. The introduction of cART has allowed for the delivery and full dose and dose intensive Chemotherapy regimens. HIV-HL patients are at increased risk for treatment related toxicities and drug – drug interactions which require careful attention.
Keywords: Hodgkin Disease, EBV, HIV associated HL
Key Message: Before the widespread use of ART. There was an estimated 310 fold increased risk for non hodgkin’s lymphoma 7.6 fold increase in Hodgkin’s disease. Among the HIV/AIDS Patients compared with other population in India there is increased frequency of HD among the HIV infected patients.
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