Title: Comparative Study of Serum Testosterone Levels in Male Patients of Type 2 Diabetes Mellites and Non Diabetics Presenting with Complaints of Sexual Dysfunction
Authors: Dr Sandeep Chowdhary, MBBS, MD (Medicine), Dr Minaj Ahmad, D.N.B (Medicine)
DOI: https://dx.doi.org/10.18535/jmscr/v5i3.99
Abstract
Background: Diabetes mellitus is the frequent cause of sexual dysfunction in males. Various studies have reported 25 – 32 % of men with Diabetes mellites complaining of sexual dysfunction.
Material and Methods: This was a prospective observational study, conducted among 100 men (aged 35-60 years) with type 2 diabetes /No Diabetes (50 cases each) and with complaints of sexual dysfunction, from June 2015 to and February May 2016.
Results: Mean age of diabetics was 44.5 ±7.9 years and non diabetics was 42.54 ± 5.63 years. 56% of Diabetics and 20 % non diabetics had lower levels of total testosterone.68% of Diabetics and 26 % non diabetics had lower levels of free testosterone. Mean serum free testosterone in diabetics was 3.2 ± 0.78 and in non diabetics was 6.2 ± 3. Mean serum FSH level in diabetics was 4.3 ± 1.2 and in non diabetics was 9 ± 1.8. Mean serum LH level in diabetics was 6.4 ± 2.1 and in non diabetics was 12 ± 2.8. Mean Prolactin levels in Diabetics and non Diabetics was 10.5 ± 2.6 and 15 ± 2.5. Mean SHBG levels in Diabetics and non – diabetics was 8.6 ± 1.8 and 16 ± 3.2. Prevalence of Hypogonadism was 22% in Diabetics and 10% in Non diabetics.
Conclusion: Hypogonadism is more prevalent in patients with Type 2 Diabetes mellites than non-diabetics. It is associated with low levels of free testosterone.
Keywords: Type 2 Diabetes Mellites, Sexual Dysfunction, Low serum total testosterone, Hypogonadism
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