Title: Retrospective Evaluation of Adverse Reactions Associated with Blood Transfusions Reported in the Blood Banks of Kerala
Authors: P. K. Sreekumar, T. M. Pramod Kumar, G. Partha Sarathi, Debasish Gupta, Pallavi
DOI: https://dx.doi.org/10.18535/jmscr/v5i3.87
Abstract
A retrospective review of all the adverse transfusion reactions reported from 01/01/2014 to 31/12/2015 by the 19 blood banks of Kerala was done with the aim to assess the frequency and type of transfusion reactions occurring in patients receiving blood transfusion. During the study period a total of 455201 units of blood products were issued from the subjected blood banks for transfusion. RBC is the major product (39.8%) issued for transfusion and under the hemovigilance system, totally 814 adverse reactions (0.18%) were reported during the study period. Among them, the most common type of reaction observed was febrile non-hemolytic transfusion reaction (FNHTR) 69.9% (n =569) followed by anaphylaxis, Post transfusion purpura (PTP), Transfusion associated dyspnoea (TAD) were also reported. No major reactions like transfusion related acute lung injury (TRALI), transfusion associated graft Vs host disease (TAGvHD), transfusion associated circulatory overload (TACO) and haemolysis were reported. No infections were also reported during the study period. From this study it was clear that the frequency of adverse transfusion reactions was 0.18%. Obivesoly, it may be due to an underestimation of the true incidence because of under reporting and it revealed that necessity of awareness development regarding with safe blood transfusion and the implementation of proper and effective haemovigilance system to provide better patient care.
Keywords: Adverse transfusion reaction, Blood transfusion, Haemovigilance.
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